DEPLETION ZONE ISOTACHOPHORESIS (dzITP): BEATING THE SIMPLICITY OF ELECTROPHORESIS

نویسندگان

  • Jos Quist
  • Kjeld Janssen
  • Paul Vulto
  • Thomas Hankemeier
  • Heiko van der Linden
چکیده

A radically novel approach towards isotachophoresis is presented in which a nanochannel-induced ionic depletion zone replaces a trailing electrolyte. This makes depletion zone isotachophoresis (dzITP) a single-electrolyte focusing and separation technique. Moreover, focusing strength and positions of analyte zones can be precisely controlled by a three-point voltage actuation scheme. Thus, dzITP provides unprecedented versatility and simplicity.

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تاریخ انتشار 2011